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49ers vs. Colts highlights: SF extends win streak to 5 games

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the ...

Colts vs. 49ers MNF takeaways

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.

San Francisco 49ers vs Indianapolis Colts recap today: Purdy's huge night buries Colts

The Indianapolis Colts lose to the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Score updates, highlights ...

49ers vs. Colts: Brock Purdy lights up Indy for 5 TDs, spoils Philip Rivers' season debut at home in 48-27 win

The Colts' loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and ...