The San Francisco 49ers may win their Week 16 matchup with the Indianapolis Colts, but they lost one of their best players to ...

San Francisco 49ers quarterback Brock Purdy completes a 3-yard touchdown pass to wide receiver Jauan Jennings.

San Francisco 49ers tight end George Kittle catches a 15-yard pass from quarterback Brock Purdy. San Francisco 49ers ...

Brock Purdy replied in kind after Philip Rivers opened the scoring with a TD pass against the 49ers. Purdy responded with 2!

The more impactful injury is Bortolini, who's since been replaced by Danny Pinter at the heart of the offensive line. The ...

The Chargers have won 11 games and are still in the hunt for an AFC West title. That doesn’t mean they are Super Bowl ready ...

Nikita Grebenkin had a goal and an assist, Carl Grundstrom also scored, and the Philadelphia Flyers beat the Vancouver ...

After a 1-yard gain by Christian McCaffrey and an incompletion from Brock Purdy, San Francisco faces third-and-goal. What a ball by Brock Purdy, leaving it where only Jauan Jennings could secure it ...

The Indianapolis Colts host the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Live score updates, highlights, where to watch.

The Sporting News is tracking live scoring updates and highlights for 49ers vs. Colts on "Monday Night Football." Follow for complete results from the NFL Week 16 prime-time game.

After making a $500,000 catch on Monday Night Football against the Colts, Kendrick Bourne had the perfect celebration in his ...

The Indianapolis Colts are looking to snap a four-game losing streak and get back into the AFC playoff picture Monday night.